Let's imagine that the Northeast Ohio healthcare innovation community is a football team. That would make business recruiter BioEnterprise the quarterback, "handing off" startup companies to Austen BioInnovation Institute in Akron, with an aim of scoring funding and resources a company needs to succeed. 
 
Strained metaphors aside, BioEnterprise and Austen are two local groups working as a team to push a regional economic transition from staid manufacturing to the more vibrant realm of healthcare and innovation technology. What exactly do these groups do and how do they do it? How do they work together to achieve their goals? Key members from each organization share their connected strategies.
 
Providing a guiding hand
 
BioEnterprise is a Cleveland nonprofit tasked with growing healthcare companies and commercializing bioscience technologies. The early-stage firms BioEnterprise assists are seeking to produce medical devices and biotechnology, or developing drugs for commercial use.
 
The economic development group was founded in 2002 by the Cleveland Clinic, University Hospitals and Case Western Reserve University as a way to harness area strengths in medical devices and healthcare technology. The nonprofit's foray into a potentially lucrative "innovation economy" is built by guiding new companies, not funding them, says interim president Aram Nerpouni.
 
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In this video, Chris Coburn, Executive Director of Cleveland Clinic Innovations, explains how the organization takes the intellectual assets of the Cleveland Clinic -- be they medical devices, diagnostics, or drugs -- and turns them into commercial products. With names like Cleveland Heart, Explorys, and Juventas Therapeutics, its track record is impressive.

When Case's think[box] is completed, it will be one of largest university-based invention centers in the world, bigger even than Stanford's d. school, MIT's Fab Lab, or Rice's Design Kitchen. It’s a venture that has the potential to play a major role in spurring innovation in the region, say local educators and entrepreneurs.

Whether it is health care, information technology, clean tech or business and consumer products, our region’s increased level of startup activity is attracting funding from venture capital firms both here in Northeast Ohio and beyond. But experts say there's a ways to go before the Silicon Valley comparisons stick.

On a recent September morning, the American Courage freighter began a trip upriver at the Port Authority’s Cleveland Bulk Terminal, where it picked up roughly 15,000 tons of iron ore. This was the 635-foot freighter’s second trip that day up the 5.5-mile ship channel to ArcelorMittal, where workers would later turn the iron ore into steel used to produce cars, construct buildings, and make household appliances.

The Cleveland-Cuyahoga County Port Authority is asking voters to vote "Yes" on Issue 108, a levy that would cost property owners roughly $20 a year per $100,000. Fresh Water discusses the importance of the levy and more with Port President and CEO William Friedman.

Several times each week, giant freighters the length of two football fields travel up the crooked Cuyahoga River to deliver raw materials. In this slide show, Fresh Water photographer Bob Perkoski goes along for the ride.

The recession pushed many people to trade in conventional careers for artistic pursuits. But establishing an arts studio or workshop is expensive and time consuming. Enter the ready-made studio. From community darkrooms and wood shops to collaborative sewing and printmaking co-ops, collaborative arts studios continue to pop up to serve the burgeoning "maker class."

If you don't know the name Scott Kim, then you likely have been missing out on some of the most thrilling food presently served in Cleveland. Kim's Shaker Square restaurant Sasa encourages exploration through a bevy of Japanese small plates. With Accent, slated to open in just weeks, the chef's culinary borders will expand past those of Japan to include influences from Korea, India, China and beyond.

When it comes to attracting talent from outside the city, Cleveland "has room for improvement," according to recruiters and other pros tasked with the job. But numerous developments currently taking place in the city are major steps in the right direction, say those same pros.

As city dwellers, we tend to focus on buildings. But it's the spaces in between those structures that matter most, say urban planners. Public spaces bring communities together, improve our physical and mental well-being, and drive social and economic change. The presence and quality of our public spaces is a measure of the desirability of a city.

Neighborhoods that experience revitalization often do so at the expense of their distinctiveness. As an area becomes more appealing, vacant spaces fill up, and higher rents crowd out all but the deepest pockets. Ohio City business owners, developers, and community development groups are fighting that with an unprecedented level of cooperation.

Thanks to crowdfunding sites like Kickstarter, entrepreneurs often overlooked by traditional investment sources are securing much-needed capital to launch their startups. In addition to raising cash, these sites are proving invaluable for testing new ideas, developing a customer base, gaining exposure, and launching ideas into a larger marketplace.

In recent years, Cleveland Municipal School District has opened 14 new high-performing public schools rated Excellent or Effective by the State. The Cleveland Plan, approved this summer by state legislators, will pave the way for even more improvements to the district's schools, making it more likely that urban parents will choose to remain in the city.

Northeast Ohio's 80-plus young professional organizations play a critical role in plugging new talent into Cleveland. Research shows that there’s a 90-day window from when people move to a city to influence them and give them reasons to stay. Once plugged in, these YPs are helping to reshape the city’s future.

High-profile projects like a wind turbine and solar panels combined with aggressive recycling and composting programs give the Tribe a green leg up on much of the competition. By using their standing in the community, the Indians are getting people to think about sustainability, alternative energy, and recycling.

What's next? It's a question we all wish we had the answer to. But for folks looking to settle down, that question undoubtedly refers to place. In this running series, Fresh Water explores emerging Cleveland neighborhoods that are primed for growth. This week, writer Joe Baur examines Slavic Village.