Arteriocyte, a leading clinical-stage biotechnology company with offices in Cleveland and Hopkinton, Mass., has been awarded a $1 million grant by the Ohio Department of Development's Third Frontier Commission. The company, which develops proprietary stem cell and tissue engineering based therapies, will use the grant for the development and commercialization of hematopoietic stem cell expansion for clinical applications.
The move is part of the Ohio Third Frontier Biomedical Program to accelerate the company's Good Manufacturing Practices (GMP) of its NANEX technology for clinical use under the product name HemaEx.
"The technology takes a small amount of stem cells and gets a large amount of stem cells," explains Adam Sorkin, Arteriocyte's director of research and development. "We are converting our existing process that is suitable for research to a process that is suitable for use in humans.".
Arteriocyte's therapies help find cures for chronic heart disease and peripheral artery disease, among other diseases.
The company, which was founded in 2004 as a spin-off out of CWRU, has seen rapid growth in the past couple of years, going from four employees to 80. The expansion will create between 15 and 20 jobs in the production facility.
Source: Adam Sorkin
Writer: Karin Connelly
Four years ago, Susan Borison and Stephanie Silverman were regular moms who were struggling to make the right choices while raising their children. Though they found plenty of resources addressing issues regarding young children, they found a void as their children reached adolescence. So the Beachwood-based moms started their own magazine, Your Teen.
"I have five kids and parenting magazines started to be irrelevant when they hit age eight," explains Borison. "I used to say to my husband, 'I want the next magazine,' and he said, 'Just do it.'"
So, with no background in journalism or publishing, the two women set out and launched Your Teen in 2008. The goal was to address the daily struggles of raising a teenager. Today, the magazine is published quarterly and goes out to 20,000 homes and is available at Barnes and Noble bookstores in Ohio, Michigan and Pennsylvania. The magazine has a staff of five, plus interns.
"We want to empower parents to feel knowledgeable and raise their kids in a way they feel comfortable," says Borison. The mag covers everything from substance abuse and sexuality to driving and mental health. They tap experts such as Ellen Rome, head of adolescent medicine and the Cleveland Clinic, and Judy Stenta of Bellfaire JCB, for insight and advice, and host panel discussions three times a year.
"We kept falling on people who wanted to help us," says Borison of the resources they have. "The generosity of sharing their time and knowledge is incredible. We just get 'yes' over and over."
Source: Susan Borison
Writer: Karin Connelly
When Zone Recreation Center's 22 acres of green space reopen next year following a $2.5 million "green" facelift, the rainwater that falls there will be reused on site, rather than being funneled into sewers to pollute our lake, rivers and streams.
"We're using it to rehydrate the park," explains Ward 15 Councilman Matt Zone, who allocated funding for the park's revitalization.
The redesigned park's water conservation features will include permeable pavers that allow rainwater to filter into the ground (unlike most parking lots or hard surfaces, which send water cascading into the nearest sewer). "Bioswales" will also capture water and direct it into rain gardens, which will be seeded with native plants that don't require a lot of mowing, chemicals or maintenance.
One area of the park will even feature a bridge traversing a rain garden, thus allowing visitors to look down into the garden and see how it works as they pass by.
Zone Rec's new splash park will also recycle and reuse its own water. A filtration system will be installed to ensure that the water is cleaned before reuse.
The recreation center is located at W. 65th Street and Lorain Avenue in the Cleveland EcoVillage, a green community that is part of Cleveland's Detroit Shoreway neighborhood. Other green-built projects in the area include new energy-efficient townhomes and single-family homes, a large community garden, and the energy-efficient RTA station on Lorain, which is a stop along the Red Line.
Recent CWRU mechanical engineering graduates Austin Schmidt and Solomon Alkhasov won the 2011 Idea Competition, sponsored by LaunchHouse and CSU's Accelerated MBA program at Nance College of Business. They created a company called Affinity Algorithms, which develops proprietary computer arbitrage software to facilitate transactions between buyers and sellers in various online marketplaces. The software provides greater liquidity and price transparency in the marketplaces.
"We are developing a suite of online software that helps the seller in fragmented marketplaces better manage inventory," explains Schmidt. Although Schmidt and Alkhasov came up with the idea from their experiences buying and selling textbooks in college, they say it can be applied to many online marketplaces.
The idea for Affinity Algorithms came about in January, they set up shop in March, and landed at LaunchHouse this month. They plan to roll out a full build of the software in September.
Students from all Northeast Ohio colleges and universities were invited to pitch a business concept to a panel of entrepreneurs, venture capitalists, CSU faculty and LaunchHouse staff. The contest primarily focused on students who had innovative ideas in the fields of software and internet technology, low-tech medical devices and clean energy.
The second winner is Ronny Shalev, also a student at Case. Shalev created a product known as an autonomous intravenous (IV) insertion tool that will be the most effective replacement for the current procedure of manual vein localization and needle insertion. Shalev's tool will completely replace the need for trained medical staff.
Contest winners were each awarded a $2,500 scholarship to the Global AMBA program along with a prize basket of support services from LaunchHouse, "Additionally, we received a $500 check from LaunchHouse, along with a bunch of services that include legal services, accounting, and free space for three months," says Schmidt. "All in all, a very comprehensive package with everything needed to get a business off the ground."
The winners will also have the opportunity to compete for up to $5000 in follow on funding.
Source: Austin Schmidt
Writer: Karin Connelly